Repair, protect and prevent hyperpigmentation

How NEORETIN and HELIOCARE 360° work together

Hyperpigmentation rarely develops from a single cause. Sun exposure, inflammation, hormonal changes and environmental stress can all stimulate excess melanin production in the skin.

Because of this, managing pigmentation effectively requires more than simply treating visible dark spots. Dermatologists often recommend a three-step strategy that focuses on repairing existing pigmentation, protecting the skin from environmental triggers and preventing new dark spots from forming.

By combining targeted skincare treatments with advanced sun protection, it is possible to support clearer, brighter and more even-looking skin over time.

Repair existing pigmentation

Once hyperpigmentation has developed, the skin benefits from ingredients that help regulate melanin production while encouraging healthy skin renewal.

NEORETIN is an advanced pigmentation control range developed by dermatology experts at Cantabria Labs. The formulations combine clinically recognised ingredients with patented technologies designed to address several stages of the pigmentation cycle.

Two of the key technologies used within the range are RetinSphere® Technology and Azelaic Acid in AOX-Tech®.

RetinSphere® Technology

RetinSphere® Technology is a patented retinoid complex that combines two powerful forms of retinol:

• Hydroxypinacolone retinoate (HPR)
• Encapsulated retinol delivered through glycospheres and microsponges

This dual-delivery system helps support skin renewal while maintaining excellent skin tolerance.

By encouraging faster skin cell turnover, RetinSphere® Technology helps disperse accumulated pigment within the skin while also improving texture and overall radiance.

Azelaic Acid in AOX-Tech®

Azelaic acid is widely recognised for its ability to regulate melanin production and calm inflammation that can contribute to pigmentation.

In NEORETIN products, azelaic acid is delivered using AOX-Tech®, a patented technology designed to enhance the ingredient’s performance.

This advanced delivery system helps azelaic acid work more effectively within the skin to:

• Reduce the appearance of dark spots
• Improve uneven skin tone
• Calm inflammation associated with pigmentation
• Support smoother, brighter skin

Together, these technologies help address both the visible appearance of pigmentation and the biological processes that contribute to it.

Products such as NEORETIN Pigment Neutraliser Serum can be used daily to support pigmentation correction while maintaining good skin tolerance.

For enhanced results, NEORETIN Pigment Corrector Peel Pads can be used weekly to promote gentle exfoliation and accelerate skin renewal.

Protect the skin from pigmentation triggers

Sun exposure is one of the most significant triggers of hyperpigmentation.

When UV radiation reaches the skin, melanocytes increase melanin production as a protective response. This process can darken existing pigmentation and contribute to the development of new dark spots.

However, research now shows that pigmentation can also be influenced by other forms of solar radiation, including:

• Visible light
• High-energy blue light
• Infrared-A radiation

For this reason, daily protection against multiple forms of radiation is essential when managing hyperpigmentation.

HELIOCARE 360°: Advanced sun protection

HELIOCARE 360° is a dermatologist-developed sun protection range designed to provide full-spectrum protection against UVA, UVB, visible light and infrared-A radiation.

Unlike traditional sunscreens that primarily focus on UV protection, HELIOCARE 360° formulations also incorporate powerful antioxidants that help neutralise free radicals generated by sunlight and environmental stress.

At the core of the range is Fernblock®+, a powerful antioxidant technology derived from the fern Polypodium leucotomos. Fernblock®+ helps protect the skin against environmental damage and supports the skin’s natural defence mechanisms.

By helping prevent the biological processes that trigger pigmentation, advanced sun protection plays a crucial role in managing hyperpigmentation.

HELIOCARE 360° Pigment Solution Fluid SPF50+

For individuals concerned with uneven skin tone or melasma, HELIOCARE 360° Pigment Solution Fluid SPF50+ has been specifically designed to support pigmentation management.

This lightweight fluid provides high-level, full-spectrum protection while also helping improve skin tone.

Key features include:

• Protection against UVA, UVB, visible light and infrared-A radiation
• A Depigmenting System combining niacinamide and ellagic acid to help regulate melanin production
• Antioxidant protection powered by ASPA-Fernblock® Technology
• Support for DNA repair and vitamin D function
• A subtle tint that helps unify the appearance of skin tone

This multi-action approach helps protect the skin from environmental triggers while also supporting a more even-looking complexion.

Prevent pigmentation from within

While topical protection is essential, environmental stress and solar radiation can also affect the skin internally.

HELIOCARE offers an additional layer of support through HELIOCARE 360° D-Plus Capsules, which work from within to help defend the skin against sun-induced damage.

Each capsule contains ASPA-Fernblock®, a powerful combination of two plant-based antioxidant technologies:

1. Fernblock®
2. Aspalathus linearis extract (ASPA)

These antioxidants help support protection against:

• UVA radiation
• UVB radiation
• Visible light
• Infrared-A radiation

The capsules are also enriched with niacinamide and vitamin D, helping support skin health while assisting in the prevention and repair of sun damage.

HELIOCARE 360° D-Plus Capsules are often recommended for individuals prone to melasma or persistent pigmentation as part of a comprehensive sun protection strategy.

A complete routine for managing hyperpigmentation

When used together, NEORETIN and HELIOCARE 360° can support a comprehensive routine designed to repair existing pigmentation while helping prevent new dark spots from forming.

Morning routine

1. Cleanse the skin with a gentle cleanser
2. Apply NEORETIN Pigment Neutraliser Serum
3. Apply HELIOCARE 360° Pigment Solution Fluid SPF50+
4. Take a HELIOCARE 360° D-Plus Capsule before sun exposure

Evening routine

1. Cleanse the skin
2. Apply NEORETIN Pigment Neutraliser Serum
3. Follow with your preferred moisturiser or nighttime treatment

Weekly treatment

Use NEORETIN Pigment Corrector Peel Pads once per week to gently exfoliate the skin and support skin renewal.

Consistency is key

Treating hyperpigmentation takes time and consistency. Because pigmentation can be triggered by sun exposure even on cloudy days, daily protection is one of the most important steps in any skincare routine.

By combining targeted pigmentation treatments from NEORETIN with the advanced environmental protection offered by HELIOCARE 360°, it is possible to improve the appearance of existing dark spots while helping prevent new pigmentation from forming.

Over time, this comprehensive approach can support a clearer, brighter and more even-looking complexion.