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★ NEWSave up to 30%+ Free Gift worth £54.99
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★ NEWSave up to 30%+ Free Gift worth £54.99
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★ NEWSave up to 30%+ Free Gift worth £54.99
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★ NEWSave up to 30%+ Free Gift worth £54.99
ENDOCARE RENEWAL Retinoid Serum
ENDOCARE RENEWAL Retinoid Serum
30ml
Earn 550 points
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FREE ENDOCARE C Ferulic with the purchase of any ENDOCARE Retinoid Serum
A clinically proven AM + PM skincare duo: antioxidant defence by day, skin renewal by night - for visibly brighter, smoother, more resilient skin.
ENDOCARE RENEWAL Retinoid Serum is a dual-retinoid serum designed to visibly smooth fine lines, refine skin texture and support firmer-looking skin. Powered by exclusive RETINDUO® Technology, it combines pure retinol in microsponges with AOX Tech-encapsulated retinal, supported by a targeted, natural booster complex to optimise bioavailability and enhance retinoid stability.
Its intelligent dual-delivery system helps optimise retinoid performance while minimising irritation. In clinical evaluation, 90% of users reported softer skin and reduced fine lines, with 85% noting improved texture after 28 days.* Enriched with cross-linked hyaluronic acid and niacinamide to support hydration and reinforce the skin barrier, this fragrance-free retinoid serum is suitable for all skin types and positioned as the first step in the ENDOCARE RENEWAL Retinoid progression.
Key information
Key information
- RETINDUO® Dual-Retinoid Technology: Combines pure retinol in microsponges with AOX Tech-encapsulated retinal for optimised skin renewal and tolerability.
- Clinically Proven Smoothing: 90% reported softer skin and visibly reduced fine lines after 28 days.*
- Refines Texture: 85% noted improved skin texture in clinical evaluation.*
- Controlled Performance with Enhanced Tolerance: Designed to maximise results while helping minimise irritation.
- Retinoid Booster Complex: Supports retinoic acid stability to enhance efficacy.
- Barrier-Supporting Formula: 4% niacinamide helps reinforce the skin barrier and improve tone.
- Long-Lasting Hydration: 3% cross-linked hyaluronic acid helps maintain moisture and comfort.
- Airless, Airtight Packaging: Preserves retinol stability for consistent performance.
- Fragrance-Free & Dermatologically Tested: Suitable for all skin types and ideal as the first step in the Renewal progression.
How to use
How to use
Usage: Apply a pea-sized amount to cleansed face and neck at night. Begin twice weekly and increase frequency gradually according to tolerance. Use daily broad-spectrum SPF. Progress through the Renewal system as advised to maximise performance before advancing to the Intensive formulation.
Cautions: For external use only. Avoid contact with eyes, the eye contour area, and mucous membranes. A mild peeling sensation may occur during the first few applications; this is normal. If irritation develops, reduce the frequency of use or discontinue application. Do not apply to irritated or broken skin. Not recommended during pregnancy or while breastfeeding. A change in colour may occur over time; this does not affect the product’s efficacy. This product contains vitamin A. Consider your total daily intake of vitamin A before use.
Ingredients
Ingredients
Key Ingredients
RETINDUO® Technology
Benefits:
Visible skin renewal, Enhanced skin comfort, Improves fine lines, Smoothes uneven texture
Niacinamide
Benefits:
Improves elasticity, Enhances barrier function, Evens skin tone, Reduces inflammation
Hyaluronic Acid
Benefits:
Deeply hydrates, Plumps skin, Reduces fine lines, Enhances elasticity
Aqua; Propanediol; Niacinamide; Sodium Carboxymethyl Starch; Undecane; Caprylic/Capric Triglyceride; Polyglyceryl-6 Distearate; Glycerin; Tridecane; Pentylene Glycol; Retinol; Retinal; Phytol; Chamomilla recutita Flower Extract; Phosphatidylcholine; Mannitol; Tocopheryl Acetate; Tocopherol; Jojoba Esters; Cellulose; Polyacrylate Crosspolymer-6; Dimethyl Isosorbide; Polyglyceryl-3 Beeswax; Cetyl Alcohol; Trisodium Ethylenediamine Disuccinate; Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate; Hexamidine Diisethionate; Diutan Gum; Polyglyceryl-10 Laurate; Sodium Hyaluronate Crosspolymer; Hesperidin; Ethylhexylglycerin; Sodium Sulfite; Citric Acid; BHT.

The ENDOCARE Approach
ENDOCARE products are formulated to deliver optimal results when used together.
The ENDOCARE Approach is built on three dermatologist-aligned pillars that address the key biological drivers of skin ageing: barrier support, antioxidant protection and epidermal renewal.
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Strengthen & repair with
AGE BARRIERENDOCARE AGE BARRIER reinforces and restores the skin barrier - the essential foundation for effective skincare and optimal results.
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Prevent & correct with
RADIANCEENDOCARE RADIANCE delivers targeted antioxidant protection to help defend against pollution and oxidative stress, supporting brighter, healthier-looking skin.
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Renew & reverse with
RENEWALENDOCARE RENEWAL supports cellular turnover to actively improve key signs of skin ageing, promoting a smoother, more youthful-looking complexion.
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Protect with
HELIOCARE 360°No skincare regime is complete without sunscreen. HELIOCARE 360° provides very high-level, full-spectrum defence against UVA, UVB, visible light, and infrared-A.
* User Test: Tolerance and Efficacy Assessment, 20 subjects with normal to combination skin (35–60 years of age), application to face once daily for 28 days. Subjective Evaluation. CRO: AlYeDerm Clinic & Research, Spain, 2025. Data on file.
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