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ENDOCARE

ENDOCARE RENEWAL Retinoid Intensive Serum

ENDOCARE RENEWAL Retinoid Intensive Serum

30ml

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£60.00
£60.00
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FREE ENDOCARE C Ferulic with the purchase of any ENDOCARE Retinoid Serum

A clinically proven AM + PM skincare duo: antioxidant defence by day, skin renewal by night - for visibly brighter, smoother, more resilient skin.

ENDOCARE RENEWAL Retinoid Intensive Serum is a high-strength retinoid serum powered by exclusive RETINDUO® Technology, combining pure retinol in microsponges with AOX Tech-encapsulated retinal, supported by a targeted natural booster complex to optimise bioavailability and enhance retinoid stability.

Designed for experienced retinol users, it delivers intensified skin renewal with enhanced tolerance to visibly reduce appearance of wrinkles, improve firmness and even texture.

This dual-retinoid formula optimises performance to visibly reduce wrinkles in as little as 4 weeks*, while improving firmness, elasticity and hydration with continued use. Enriched with niacinamide and cross-linked hyaluronic acid to support the skin barrier, this fragrance-free retinol serum offers corrective results without compromising comfort.

Key information

  • RETINDUO® Dual-Retinoid Technology: Combines pure retinol in microsponges with AOX Tech-encapsulated retinal for intensified skin renewal. 
  • Clinically Proven Wrinkle Reduction: Clinically proven to visibly reduce the appearance of wrinkles in as little as 4 weeks.* 
  • Improves Skin Quality: Improves firmness, elasticity, hydration and overall skin texture.* 
  • Significant skin improvements in 10 days: Clinically proven to boost collagen, elastin and epidermal thickness.** 
  • Renewed, Repaired & Brighter Skin: 90% of users reported renewed, repaired and brighter skin.*** 
  • Reduced Fine Lines & Wrinkles: 85% of users reported reduced fine lines and wrinkles.*** 
  • Barrier-Supporting Formula: 4% niacinamide to help reinforce the skin barrier. 
  • Hydration Support: Contains 3% cross-linked hyaluronic acid to maintain moisture and comfort. 
  • Airless, Airtight Packaging: Preserves retinol stability for consistent performance.  
  • Fragrance-Free & Dermatologically Tested: Suitable for experienced retinoid users. 

How to use

Usage: Apply a pea sized amount to cleansed skin on face and neck at night. Begin usage twice weekly and increase application frequency as per tolerance. Avoid direct sun exposure and use a broad-spectrum sunscreen such as HELIOCARE.

Cautions: For external use only. Avoid contact with eyes, the eye contour area, and mucous membranes. Mild peeling may occur during the first few applications; this is normal. If irritation develops, reduce frequency of use or discontinue application. Do not apply to irritated or broken skin. Not recommended during pregnancy or while breastfeeding. A change in colour may occur over time; this does not affect the product’s efficacy. Contains vitamin A. Consider your total daily intake of vitamin A before use. Not recommended for sensitive skin.

Ingredients

Key Ingredients

RETINDUO® Technology

RETINDUO® is an exclusive dual-retinoid system that combines pure retinol in microsponges with AOX Tech-encapsulated retinal, supported by a targeted natural booster complex to optimise bioavailability, enhance retinoid stability and deliver powerful yet controlled skin renewal enhancing stability and skin comfort.

Benefits:

Visible skin renewal, Enhanced skin comfort, Improves fine lines, Smoothes uneven texture

Hyaluronic Acid

Hyaluronic Acid is a powerful humectant that attracts and retains moisture in the skin. It deeply hydrates, plumps the skin, reduces fine lines, and enhances skin elasticity.

Benefits:

Deeply hydrates, Plumps skin, Reduces fine lines, Enhances elasticity

Niacinamide

Niacinamide, also known as Vitamin B3, is a versatile skincare ingredient that improves skin elasticity, enhances barrier function, evens skin tone, and reduces inflammation.

Benefits:

Improves elasticity, Enhances barrier function, Evens skin tone, Reduces inflammation

All ingredients

Aqua; Propanediol; Niacinamide; Sodium Carboxymethyl Starch; Undecane; Caprylic/Capric Triglyceride; Polyglyceryl-6 Distearate; Glycerin; Pentylene Glycol; Dimethyl Isosorbide; Tridecane; Retinol; Retinal; Chamomilla recutita Flower Extract; Jojoba Esters; Phytol; Tocopheryl Acetate; Tocopherol; Cellulose; Polyacrylate Crosspolymer-6; Polyglyceryl-3 Beeswax; Cetyl Alcohol; Mannitol; Phosphatidylcholine; Trisodium Ethylenediamine Disuccinate; Polyglyceryl-10 Laurate; Citric Acid; Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate; Diutan Gum; Hesperidin; Ethylhexylglycerin; Sodium Hyaluronate Crosspolymer; Sodium Sulfite; BHT; Hexamidine Diisethionate.

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The ENDOCARE Approach

ENDOCARE products are formulated to deliver optimal results when used together.

The ENDOCARE Approach is built on three dermatologist-aligned pillars that address the key biological drivers of skin ageing: barrier support, antioxidant protection and epidermal renewal.

  • Strengthen & repair with
    AGE BARRIER

    ENDOCARE AGE BARRIER reinforces and restores the skin barrier - the essential foundation for effective skincare and optimal results.

  • Prevent & correct with
    RADIANCE

    ENDOCARE RADIANCE delivers targeted antioxidant protection to help defend against pollution and oxidative stress, supporting brighter, healthier-looking skin.

  • Renew & reverse with
    RENEWAL

    ENDOCARE RENEWAL supports cellular turnover to actively improve key signs of skin ageing, promoting a smoother, more youthful-looking complexion.

  • Protect with
    HELIOCARE 360°

    No skincare regime is complete without sunscreen. HELIOCARE 360° provides very high-level, full-spectrum defence against UVA, UVB, visible light, and infrared-A.

* In vivo study conducted on 40 females aged 35-60 to evaluate the efficacy and tolerance of a new retinoid combination with the equivalent retinol concentration in the treatment of skin aging. Data on file.
* Ex vivo clinical study conducted on photoaged skin explants. Compared healthy skin, aged skin, 0.5% retinol and RetinDuo 0.3%. Analysed collagen, elastin and epidermal thickness after 10 days. Data on file.
** Tolerance and Efficacy Assessment, 20 subjects with normal to combination skin (35–60 years of age), application to face once daily for 28 days. Subjective Evaluation. CRO: AlYeDerm Clinic & Research, Spain, 2025. Data on file.